Jean Bosser

  • Un coeur sec

    Jacques Bosser

    Peu après le décès de son père, Pierre, la cinquantaine, reçoit un appel d'une femme qui se présente comme sa demi-soeur. Née durant la dernière guerre, Claire n'a jamais vraiment connu ses parents. Hésitant devant la révélation d'un secret familial, Pierre, accepte néanmoins de la rencontrer pour trouver, peut-être, des réponses aux questions qu'il se pose depuis si longtemps sur lui-même.
    Il veut comprendre son histoire, le pourquoi de son apprentissage forcé d'une vie solitaire, de son incapacité à aimer. Aux côtés de Claire, il découvre la raison de sa naissance, apprend à mieux se connaître, lui qui continue de souffrir de son enfance dénuée de toute affection.
    Un Coeur sec dresse le portrait désenchanté, touchant, mais aussi mordant et drôle, d'un individualiste sans attaches, observateur attentif et amusé de sa vie, de la vie.

  • This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in Escherichia coli, which focuses on the control of  activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested.Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of  DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replication initiation may differ depending on growth conditions. Therefore, understanding the regulation of DNA duplication requires placing this process in the context of the current knowledge on bacterial metabolism, as well as cellular and chromosomal structure. Moreover, in both Escherichia coli and eukaryotic cells, replication initiator proteins were shown to play other roles in addition to driving the assembly of replication complexes, which constitutes another, yet not sufficiently understood, layer of coordinating DNA replication with the cell cycle.

  • Cet ouvrage est une réédition numérique d'un livre paru au XXe siècle, désormais indisponible dans son format d'origine.

  • Research-based advice for people who care for someone with dementia Nearly half of U.S. citizens over the age of 85 are suffering from some kind of dementia and require care. Loving Someone Who Has Dementia is a new kind of caregiving book. It's not about the usual techniques, but about how to manage on-going stress and grief. The book is for caregivers, family members, friends, neighbors as well as educators and professionals-anyone touched by the epidemic of dementia. Dr. Boss helps caregivers find hope in "ambiguous loss"-having a loved one both here and not here, physically present but psychologically absent. Outlines seven guidelines to stay resilient while caring for someone who has dementia Discusses the meaning of relationships with individuals who are cognitively impaired and no longer as they used to be Offers approaches to understand and cope with the emotional strain of care-giving Boss's book builds on research and clinical experience, yet the material is presented as a conversation. She shows you a way to embrace rather than resist the ambiguity in your relationship with someone who has dementia.

  • Découvrez cette nouvelle issue du collectif Ténèbres 2016. En coédition avec Dreampress.

  • Cet ouvrage est une réédition numérique d'un livre paru au XXe siècle, désormais indisponible dans son format d'origine.

  • AARP Digital Editions offer you practical tips, proven solutions, and expert guidance. In Loving Someone Who Has Dementia, Pauline Boss provides research-based advice for people who care for someone with dementia. Nearly half of U.S. citizens over the age of 85 are suffering from some kind of dementia and require care. Loving Someone Who Has Dementia is a new kind of caregiving book. It's not about the usual techniques, but about how to manage on-going stress and grief. The book is for caregivers, family members, friends, neighbors as well as educators and professionals-anyone touched by the epidemic of dementia. Dr. Boss helps caregivers find hope in "ambiguous loss"-having a loved one both here and not here, physically present but psychologically absent. Outlines seven guidelines to stay resilient while caring for someone who has dementia Discusses the meaning of relationships with individuals who are cognitively impaired and no longer as they used to be Offers approaches to understand and cope with the emotional strain of care-giving Boss's book builds on research and clinical experience, yet the material is presented as a conversation. She shows you a way to embrace rather than resist the ambiguity in your relationship with someone who has dementia.

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